One Platform. Many Applications.
BioThera isolates and characterizes plant-derived extracellular vesicles at manufacturing scale. What those vesicles are formulated into is an application question, not a platform one. Below are the areas the platform is built to serve — and how far each one has actually gone.
Characterized material, documented batch by batch.
Material
Characterized EV bulk
Plant-derived extracellular vesicles isolated at manufacturing scale, counted by Nanoparticle Tracking Analysis and characterized against the MISEV2023 marker framework.
Documentation
Batch-specific CoA
Every batch ships with its own Certificate of Analysis: particle concentration, EV marker panel, and contamination screen. MISEV2023 disclosures available on request.
Logistics
Cold-chain delivery
Shipped directly from the BioThera Solutions facility in Ottawa, Ontario, in cold-chain packaging sized to the destination. No distributor handoff.
Where the platform applies — and how far it has gone.
Maturity reflects how far BioThera has taken each area, not what extracellular vesicles are claimed to do in the literature. Areas marked as research directions have no BioThera product and no published timeline.
Skincare & dermocosmetics
Topical formulation of characterized plant-derived EVs for professional skin care. Supplied to verified dermatology and aesthetic medicine clinics in Canada under our Vesera™ brand. Not in general distribution.
Clinical dermatology
An active safety and efficacy study is underway with practicing dermatologist partners. Clinics evaluating the material receive the batch-specific Certificate of Analysis behind every shipment.
Wound & barrier repair
EV cargo classes associated with wound healing appear in our proteomics data and in the plant-EV literature. We have characterization data; we do not yet have outcome data.
Regenerative medicine
The biomanufacturing and characterization requirements of regenerative applications are the ones this platform was engineered against. No BioThera product exists in this space.
Drug delivery
EVs are a phospholipid-bilayer delivery vehicle. Whether ours can carry an exogenous payload at specification is an open question we are equipped to answer.
Vesera™ — our dermocosmetic brand.
Vesera™ is BioThera’s dermocosmetic brand: plant-derived extracellular vesicles from Aloe barbadensis, formulated for professional skin care. It is a Health Canada-notified cosmetic, characterized to MISEV2023 on every batch. Vesera™ is one application of the platform — not the company.
Standards we manufacture to
Health Canada — Cosmetic Regulations (C.R.C., c. 869)
Fully compliant with Canada's Cosmetic Regulations under the Canada Consumer Product Safety Act (C.R.C., c. 869). Canadian market authorized.
MISEV2023 — Characterization Compliant
Fully compliant with the Minimal Information for Studies of Extracellular Vesicles (MISEV2023) guidelines — the global standard published by the International Society for Extracellular Vesicles (ISEV).
Leaping Bunny Cruelty-Free Certification
Active certification. No animal testing at any stage of production or supply chain.
GMP/ISO-Aligned Manufacturing
Manufacturing process under active development toward GMP and ISO alignment as we scale our dermocosmetic and EV-based skincare portfolio.
FDA — FD&C Act / MoCRA Alignment
Formulation is aligned with the Federal Food, Drug, and Cosmetic Act (FD&C Act, 21 U.S.C. § 361) and the Modernization of Cosmetics Regulation Act of 2022 (MoCRA). U.S. market entry is planned for a future phase — facility registration and full MoCRA compliance will be pursued at that time.
Be First.
The Vesera™ Serum is in active clinical evaluation — not yet in general distribution. Join the early access list and we will notify you the moment clinic access opens. Tell us who you are so we can prioritize the right pathway.
BioThera supplies cosmetic-grade material today. Vesera™ is a cosmetic under Health Canada Cosmetic Regulations and is not intended to diagnose, treat, cure, or prevent any disease. Application areas marked as research directions are not products, are not offered for sale, and carry no therapeutic claim.
Talk to us about supply or co-development.
Whether you need characterized EV material with documentation behind it, or want to explore an application that is not on this page, start with a conversation.
Contact the team